Medical Pioneer. He was the co-discoverer of insulin. Born in West Pembroke, Maine, of Canadian parents, while studying medicine at the University of Toronto, he came to meet and become the assistant to Sir Frederick Banting in 1921, who was working on the extract of insulin, which controls the detrimental affects of diabetes. For Charles Best's work, Banting shared half of the credit and monies from his Nobel Prize in physiology and medicine. During World War II, he was influential in starting a program in the use of dried blood serum. He became the director of the University of Toronto's Banting-Best Department of Medicine Research after Sir Banting's untimely death in 1941. He also gained fame for investigating the properties of the anti-coagulant agent heparin.