The son of Michele Forgione (born at Pietrelcina, Kingdom of Naples in 1819, who married twice, the second time to Felicita D'Andrea, at Pietrelcina on September 23, 1859, and died in Pietrelcina, on August 29, 1867, aged 48), and his wife Felicita (born around 1839, and died in Pietrelcina on October 21, 1887, aged 48), Grazio "Orazio" Forgione was born in Pietrelcina, Benevento, Italy, on October 22, 1860, and married at Pietrelcina on June 8, 1881, at 20 years of age.
A peasant farmer, he died at San Giovanni Rotondo, Foggia, on October 8, 1946, aged 86. Grazio went to the United States of America in search of work to pay for private tutoring for his son Francesco, so that he might meet the academic requirements to enter the Capuchin Order. It was in this period that Francesco received the sacrament of Confirmation on September 27, 1899.
Together with his wife Maria Giuseppa "Beppa" Di Nunzio, Orazio fathered Michele, Francesco, Felicita, Pellegrina, Grazia, and two other children Francesco and Amalia, who died in infancy.
Michele married Giuseppa Cardone (1884 - 1946), and died at San Giovanni Rotondo on May 9, 1967, aged 85. Michele and Giuseppa had 8 children, all of whom died at birth on early in infancy, except Francesco Forgione (who was born in Pietrelcina on March 18, 1909, and died at Pietrelcina on November 9, 1920, of meningitis, at age 11), and Pia Forgione (born in Pietrelcina on January 6, 1924, married at San Giovanni Rotondo in 1945, to Mario Pennelli, parents of eight children).
Francesco Forgione - Saint Padre Pio of Pietrelcina - born in Pietrelcina, Benevento, Italy, on May 25, 1887; died at San Giovanni Rotondo, Foggia, Italy, on September 23, 1968, at age 81; canonized by Pope John Paul II on June 16, 2002.
Felicita Forgione - born in Pietrelcina on September 15, 1889; married on October 20, 1910, to Vincenzo Masone (1886 - 1941); died in Pietrelcina on September 25, 1918, of Spanish flu, complicated by a miscarriage at age 29. Felicita and Vincenzo had the following children: Giuseppa Masone (who was born at Pietrelcina on February 4, 1912, died at Arco di Trento December 18, 1930, of tuberculosis aged 18); Pellegrino Masone (born in Pietrelcina on July 25, 1914, died in Pietrelcina September 22, 1918, of the Spanish flu, aged 4); Ettore Masone (born in Pietrelcina on December 1, 1916; married Mariuccia Ghislieri at Loreto 1961; had one son, Pio Masone, born 1963; died at Benevento around 1978, aged 62).
Pellegrina Forgione - born in Pietrelcina on March 15, 1892; married July 26, 1913, to Antonino Masone; died at Chieti February 19, 1944, of injuries received in a World War II bombing raid, aged nearly 52. Pellegrina Forgione and Antonino had one child: Maria Giuseppa (died at age 3-1/2 on March 2, 1917); Alfredo (who died in the influenza epidemic at age 14 months October 12, 1918) was allegedly illegitimate.
Grazia Forgione (Sister Pia of Our Lady of Sorrows) - born in Pietrelcina on December 26, 1894, who died in Rome after a lengthy illness on April 30, 1969, aged 74.