María Manuela Dorotea Valenzuela y Serrano was the daughter of Ramón Valenzuela y López and María Ascención Serrano y Navarro. She was baptized at Mission San Gabriel, Alta California, México, on August 1, 1844 (SG Baptism 08694). She married (1) Julian Váldez y [López? Reyes? Morillo?] at the Los Angeles Plaza Church on October 12, 1861. Julian died sometime before 1865, after which she married (2) Ramón Chávez y González at the Los Angeles Plaza Church on August 14, 1865. Ramón died before December 1878, since she appears as a widow living at 216 San Pedro Street, Los Angeles, on June 10, 1880 (1880 US Census). After Ramón's death she married (3) José Antonio Esteban Machado y Palomares in late 1880 or early 1881. She died at her home in Palms, Los Angeles County.
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Children:
(with Váldez)
-
-

(with Chávez)
- (twin) Zenaída Soíla (May 7, 1866-Dec. 8, 1905; m. Diego Alcalá Machado y Talamantes)
- (twin) Cleotilde (May 7, 1866-Aug. 25, 1940; m. Joseph I. M. Spencer [1859-1944])
- María Ignacia (1868-19??; m. John F. Spencer [1865-19??])
- Antonio Francisco* (Apr. 2, 1874-Feb. 11, 1939, L.A.; m. Antonia Maria Villa)
- Cristobal S.* (1875-1945; m. Luísa Oliveras y Rubio)

(with Machado)
- Manuela Emma (1879-1966; m. Allen H. Letton)
- Adela Viviana (Dec. 2, 1885-1971; m. Porfirio Domínguez)
- Ignacio Antonio (Jan 29, 1888-Jun. 7, 1965; m. Delfina Talamantes)
- Estefana "Effie" E. (Aug. 22, 1890-Jul. 6, 1980; m. José Valenzuela y R...)

* Assumed Machado surname
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DEATHS.
MACHADO-At Ballona, at her home, Mrs. Manuela Valenzuela Machado, aged 52 years. Funeral at 2 p.m. today from the family residence at Ballona.
(Los Angeles Times; Oct. 3, 1895)
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MANUELA V. DE MACHADO, R. E. P.
Falleció el 2 del corriente a las 12 del día después de una larga y penosa infermidad a la edad de 51 años 8 meses, 8 días; su funeral estuvieron lugar el día siguiente en el Cementerio Católico de Santa Mónica. Su afejido esposo y demás deudos dan las gracias a todos los que se servieron a acompanaria a su ultima morada. Ramón Valenzuela, padre; Ascención S. de Valenzuela, madre; Antonio Machado, Esposo.
Hijos: Antonio Machado; Cristobal Machado; Ygnacio Machado.
Hijas: Zenaída C. de Machado; Cleotilde C. de Spencer; María Ygnacia de Spencer; Emma Machado; Adela Machado; Estefana Machado.
Hermanos: Juvencio Valenzuela; Gaspar Valenzuela; José Valenzuela; Ramón Valenzuela; Arnulfo Valenzuela.
Hermanas: Felipa V. de Reyes; Salvadora V. de Ruís; Clotilde V. de Ibarra; Ascención Valenzuela.
Hermanos Politicos: Andrés Machado; Rafael Machado; Cristobal Machado.
Hermanas Politicos: Luísa M. de Cháves; Bersabe M. de Cháves,
Hijos Politicos: Alcalá Machado; Joe Spencer; John Spencer.

(MANUELA V. DE MACHADO, Rest in Peace. She died on the 2nd of October at 12 noon after a long and painful illness at the age of 51 years, 8 months, 8 days [Jan. 24, 1844]; her funeral took place the following day at the Catholic Cemetery in Santa Monica. Her affectionate husband and other relatives thank all those who served to accompany her to her final resting place.
Ramón Valenzuela, father; Ascención [Serrano] de Valenzuela, mother; Antonio Machado, Husband.
Sons: Antonio Machado; Cristobal Machado; Ygnacio Machado.
Daughters: Zenaída [Chávez] de Machado; Cleotilde [Chávez] de Spencer; Maria Ygnacia [Chávez] de Spencer; Emma Machado; Adela Machado; Estefana Machado.
Brothers: Juvencio Valenzuela [LA Baptism 01558]; Gaspar Valenzuela; José Valenzuela; Ramón Valenzuela; Arnulfo Valenzuela.
Sisters: Felipa [Valenzuela] de Reyes [LA Baptism 01814]; Salvadora [Valenzuela] de Ruíz; Clotilde [Valenzuela] de Ibarra; Ascención Valenzuela.
Brothers-in-Law: Andrés Machado; Rafael Machado; Cristobal Machado.
Sisters-in-Law: Luísa Machado de Chávez; Bersabe Machado de Chávez,
Children-in-Law: Alcalá Machado; Joe Spencer; John Spencer.)
(Dos Republicas [Los Angeles], October 12, 1895)