He was married to Hattie Urbanna Williams on November 20, 1879 in Orangeburg County, South Carolina.

In the 1880 census, Edwin was living in Elizabeth Township, Orangeburg County, South Carolina. He was listed as, Edwin L. Culler, a farmer, age 24 born in South Carolina, and his wife, Hattie Culler, age 19 born in South Carolina, also living with them were Edwin's sister-in-law, Anna D. Culler, keeping house, age 33, born in South Carolina, and her two sons, Oscar H. Culler, age 12, and Edgar M. Culler, age 10, both listed born in South Carolina.

In the 1900 census taken on June 1, Edwin and his family were living in Elizabeth Township, Orangeburg County, South Carolina. He was listed as Edwin L. Culler, a farmer, age 44, born October 1855 in South Carolina, his wife, Hattie U. Culler, age 39, born September 1860, in South Carolina, their children listed were; Edwin L. Culler, age 17, born June 1882, Hayne W. Culler, age 15, born January 1885, Agnes H. Culler, age 10 born November 1889, John C. Culler, age 7 born January 1893, Leon R. Culler, age 3 born May 1897, and Hugh Culler age 1 month, born April 1900, all listed born in South Carolina.

In the 1910 census taken April 19, Edwin and his family were living in Limestone Township, Orangeburg County, South Carolina. He was listed as, Edwin L. Culler, a general farmer, age 54 born in South Carolina, and his wife, Hattie U. Culler, age 49 in South Carolina, and their children listed were; Edwin L. Culler Jr. age 27, Hattie Agnes Culler age 20, John Cahoun Culler age 17, Leon Ryon Culler age 12, Hugh Clayton Culler age 10, Robert Lee Culler age 7, and Amie A. Culler age 4, all listed born in South Carolina.

In the 1920 census taken on January 19, Edwin and his family were living in Limestone Township, Orangeburg County, South Carolina. He was listed as, a general farmer, age 64 born in South Carolina, and his wife, Hattie U. Culler, age 59 born in South Carolina, and their children still living at home were; Hugh C. Culler, age 19, and Anna U. Culler age 13, both born in South Carolina.

According to his death certificate he was listed as, Edwin L. Culler, a white male, a farmer, age 65, born in South Carolina. His parents were listed as, Jacob W. Culler, and Sarah Inabnit, both born in South Carolina. He died in Baptist Hospital, in Columbia, Richland County, South Carolina, of Pylon's Obstruction, that he had for about 5 weeks, on December 4, 1920. Place of burial was Orangeburg, South Carolina, on December 5, 1920. The informant was his son, Edwin L. Culler, of Wolfton, South Carolina.

Information researched by Richard Paul Culler, of Carrollton, Ohio.