Son of William Griffith Jr. (1697-1757) and Comfort Duvall Who settled in Montgomery county (then Frederick County) in circa 1734.∼Orlando Griffith wrote his will 10 Sep 1800, Frederick County, MD, and mentions his wife and all of his children:First I give unto my wife Elisabeth Griffith…
Unto my Son Orlando Griffith…
Unto my Son Elisha Griffith…
Unto my son Zadock Griffith…
Unto my son Chisholm Griffith…
Unto my son Joshua Griffith…
Unto my said daughter Elisabeth Griffith…
Unto my daughter Rachel Griffith…
Unto my daughter Ann Silver…
Unto My said Son William Griffith …
Unto my Son John Griffith
Frederick County July 31 1801 then came John Coons Roger Edmonston Jerome Plummer witnesses to the afore going last will and Testament of Orlando Griffith late of Frederick County Deceased and made oath...
In request of the said Jerome Plummer and that they did also see Georg Silver the other subscribing witness make his mark to which his name is perceved as a
witness to said will in the presence and at the request of the Testator and all in the presence of each other.
George Murdock Reg.r
I Elisabeth Griffith Widow of Orlando Griffith late of Frederick County Deceased do hereby renounce and quit all Claim to my Bequest or Devise made tome by the last Will of my Husband exhibited and proved according to Law and I
Elect to Take in lieu thereof my Dower or legal Share of the Estate of my said Husband-
Elisabeth [x] Griffith
July 31 Day 1801
To the Register of Wills
Fred Cormty

Elisabeth Griffith, electing instead to invoke her Dower rights, or legal share, in this particular instance afforded Elisabeth a lifetime interest in 1/3 of all land owned by her husband. -Allie Griffith-Nelson 2007.
Three of Orlando and Elizabeth's sons fought in the Revolution:Elisha,Zadock and Chisholm.
Some confusion (his wife Elizabeth Riggs?) but seems to be Elizabeth Gaither, who was apparently listed as wife of Dr Orlando Griffith.