Married to William H Gregory around 1863.

William and Charlotte were the parents of:
Anna M Gregory Wright(1864-d.bef 1903) m.1887 Edgar Wright
Charles W Gregory(1866-unk)
Laura F Gregory
Franklin Wilson Gregory(1871-27 Apr 1934)
Sarah Ella Gregory
Maude Gregory Anderson
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1870 United States Federal Census
Name: Sarah Gregory
Age in 1870: 29
Birth Year: abt 1841
Birthplace: Pennsylvania
Dwelling Number: 40
Home in 1870: Johnson, Webster, Iowa
Race: White
Gender: Female
Post Office: Fort Dodge
Household Members Age
W H Gregory 30
Sarah Gregory 29
Anna Gregory 6
Charles Gregory 4
Laura Gregory 2

1880 United States Federal Census
Name: Charlotte Gregory
Age: 38
Birth Year: abt 1842
Birthplace: Pennsylvania
Home in 1880: Reeve, Franklin, Iowa
Race: White
Gender: Female
Relation to Head of House: Wife
Marital Status: Married
Spouse's Name: William Gregory
Father's Birthplace: Pennsylvania
Mother's Birthplace: New Jersey
Occupation: Keeping House
Household Members:
Name Age
William Gregory 39
Charlotte Gregory 38
H. Anna Gregory 16
Charles W. Gregory 14
Laura F. Gregory 12
Franklin W. Gregory 9
Ella Gregory 6
Manda Gregory 3

Iowa, Cemetery Records, 1662-1999
Name: Charlotte Gregory
Birth Date: abt 1841
Death Date: 11 Nov 1883
Age: 42
Burial Location: Geneva, Franklin
Cemetery: Lindenwood
Source: Grave Records of Franklin County, Iowa
Page Number: 31
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Iowa, U.S., State Census Collection, 1836-1925
Name: William Gregory
Age: 45
Birth Year: abt 1840
Birth Place: Pennsylvania
Residence Date: 1885
Residence Place: Reeve, Franklin, Iowa, USA
Gender: Male
Marital status: Widowed
Household Members:
Name Age
William Gregory 45
Anna Gregory 21
Charles Gregory 18
Laura Gregory 16
Franklin Gregory 14
Ella Gregory 11
Maud Gregory 8